The filament will load better if you cut it at an angle. This doesn't really matter on the larger spools, but when you get down to your last 100-200 grams of filament the spools are wound so tight that it wants to curve instead of going straight into the guide hole.
LIKE I SAID "Simple Tip"
For most of you guys/girls it might be a stupid tip, but it would of saved me 10 minutes of frustration.